Heather A Leitch Selected Research

Chelation Therapy (Therapy, Chelation)

9/2019	Hematologic improvement with iron chelation therapy in myelodysplastic syndromes: Clinical data, potential mechanisms, and outstanding questions.
1/2019	Delayed time from RBC transfusion dependence to first cardiac event in lower IPSS risk MDS patients receiving iron chelation therapy.
1/2018	Iron chelation therapy in lower IPSS risk myelodysplastic syndromes; which subtypes benefit?
1/2018	Iron overload in lower international prognostic scoring system risk patients with myelodysplastic syndrome receiving red blood cell transfusions: Relation to infections and possible benefit of iron chelation therapy.
10/2017	Overall survival in lower IPSS risk MDS by receipt of iron chelation therapy, adjusting for patient-related factors and measuring from time of first red blood cell transfusion dependence: an MDS-CAN analysis.
6/2016	Hematologic improvement with iron chelation therapy in acquired anemias.
1/2015	Durable Red Blood Cell Transfusion Independence in a Patient with an MDS/MPN Overlap Syndrome Following Discontinuation of Iron Chelation Therapy.
11/2012	Improved survival with iron chelation therapy for red blood cell transfusion dependent lower IPSS risk MDS may be more significant in patients with a non-RARS diagnosis.
1/2011	Optimizing therapy for iron overload in the myelodysplastic syndromes: recent developments.
1/2011	Controversies surrounding iron chelation therapy for MDS.

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Heather A Leitch Research Topics

Disease

12	Iron Overload 07/2021 - 12/2007
11	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2021 - 12/2007
4	Infections 01/2018 - 12/2004
3	Anemia 06/2016 - 02/2013
3	Acquired Immunodeficiency Syndrome (AIDS) 01/2012 - 09/2007
3	Neoplasms (Cancer) 04/2010 - 06/2005
2	Lymphoma (Lymphomas) 09/2007 - 09/2004
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2019
1	Hemolysis 04/2018
1	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 04/2018
1	Thrombosis (Thrombus) 04/2018
1	HIV Infections (HIV Infection) 01/2018
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2018
1	Hematologic Neoplasms (Hematological Malignancy) 05/2017
1	Fatigue 01/2016
1	Frailty 01/2016
1	Castleman Disease (Castleman's Disease) 05/2015
1	Body Weight (Weight, Body) 12/2013
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2012
1	beta-Thalassemia (Cooley's Anemia) 01/2011
1	Hodgkin Disease (Hodgkin's Disease) 04/2010
1	Primary Myelofibrosis (Myelosclerosis) 03/2010
1	Cytopenia 01/2010
1	Leukemia 04/2009
1	Multiple Myeloma 08/2008
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 06/2005
1	Latent Infection 12/2004
1	Pathologic Complete Response 09/2004
1	Disease Progression 09/2004
1	Plasmablastic Lymphoma 09/2004
1	Pancytopenia 11/2003
1	Rheumatoid Arthritis 11/2003
1	Sepsis (Septicemia) 11/2003
1	Aplastic Anemia (Anemia, Hypoplastic) 11/2003

Drug/Important Bio-Agent (IBA)

13	IronIBA 09/2019 - 12/2007
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2021
1	eculizumab FDA Link 04/2018
1	BilirubinIBA 04/2018
1	Complement System Proteins (Complement)IBA 04/2018
1	Inositol (Myoinositol)IBA 04/2018
1	HaptoglobinsIBA 04/2018
1	Antifungal AgentsIBA 01/2018
1	Antiviral Agents (Antivirals)IBA 01/2018
1	ibrutinibIBA 01/2018
1	Erythropoietin FDA Link 12/2017
1	Azacitidine (5 Azacytidine)FDA Link 11/2016
1	Ferritins (Ferritin)IBA 11/2016
1	HematinicsIBA 01/2016
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2013
1	Thalidomide (Thalomid)FDA Link 02/2013
1	Immunomodulating AgentsIBA 02/2013
1	Lenalidomide (CC 5013)FDA Link 02/2013
1	Inosine Triphosphate (ITP)IBA 01/2012
1	Deferasirox FDA Link 12/2010
1	Protease Inhibitors (Protease Inhibitor)IBA 04/2010
1	AntigensIBA 06/2005
1	Neoplasm Antigens (Tumor Antigens)IBA 06/2005
1	DNA (Deoxyribonucleic Acid)IBA 12/2004
1	Etanercept (Enbrel)FDA Link 11/2003
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2003

Therapy/Procedure

13	Chelation Therapy (Therapy, Chelation) 09/2019 - 12/2007
5	Erythrocyte Transfusion 07/2021 - 01/2010
4	Therapeutics 05/2015 - 09/2004
4	Highly Active Antiretroviral Therapy (HAART) 01/2012 - 09/2004
2	Stem Cell Transplantation 01/2018 - 01/2011
1	Hematopoietic Stem Cell Transplantation 05/2017
1	Activities of Daily Living (ADL) 01/2016
1	Drug Therapy (Chemotherapy) 04/2010
1	Induction Chemotherapy 04/2009
1	Salvage Therapy 08/2008
1	Combination Drug Therapy (Combination Chemotherapy) 09/2004